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Oral administration of candesartan ameliorates chronic neuroinflammation-induced behavioral changes and apoptosis by inhibiting Ang II-induced NF-B inflammatory signaling and enhancing the phosphorylated CREB and BDNF expression level in the cortex and hippocampus regions (133)

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Changes in cytokine secretion profiles may affect the regulation of immune responses, inflammation, and immune cell communication (85)

Yosipovitch G, Sackett-Lundeen L, Goon A, Yiong Huak C, Leok Goh C, Haus E (2004) Circadian and ultradian (12 h) variations of skin blood flow and barrier function in non-irritated and irritated skin-effect of topical corticosteroids